Due to the narrow, long distance, connectivity and other characteristics of the urban integrated pipe corridor, the fire causes are complex, the fire risk is high, the evacuation difficulty is high, which makes the design of the integrated pipe corridor fire alarm system is particularly important. Based on the design of the fire alarm system of the comprehensive pipe gallery in a city, this paper introduces the setting principles of the setting of fire detectors in different compartments of the comprehensive pipe gallery, the electrical fire monitoring system, the fire door monitoring system, the gas fire extinguishing system, etc. Combining theory with practice, the application of automatic fire alarm system in comprehensive pipe gallery is expounded and analyzed.