The subsystem coordination of traditional architectural design methods needs to be improved. Therefore, an intelligent building design method based on the concept of system integration is proposed. The centralized, efficient and convenient management of intelligent building equipment subsystem is realized by using system integration technology. From the perspective of architectural design, the use requirements is considered, and the function of each subsystem is integrated and matched to improve the service quality of the building. The impact of the installation and use process of each subsystem on the building is analyzed from the aspects of space, timeliness and ease of use, so as to form an intelligent building design method to effectively reduce the adverse effects of subsystem devices, lines and equipment.