This paper mainly describes a new type of high-level laboratory intelligent management system (hereinafter referred to as "new management system"): Based on perception layer technology, the laboratory building information, biosecurity facilities, experimental equipment, intelligent equipment, personnel, materials, experimental activities, automatic control systems and so on will be formed into a data and edge calculation. Data layer is formed based on network layer transmission, and information support application layer is formed based on data layer analysis and processing, so as to build BIM control operation and maintenance system and experimental business simulation system. It aims to solve the problem that the existing central control system + experimental activity LIMS system does not have intelligent research and judgment decision-making and dynamic response, and improve the level of dynamic safety, management efficiency, operation energy consumption and intelligent decision-making of high-level biosafety laboratories.