The intelligent weak current system is an important part of the hospital building. It must be combined with the daily business management and medical technical work needs, and relatively mature technical means must be adopted to improve the information level of the hospital. This paper will study the application of intelligent weak current system in a hospital building in Weifang City, take actual engineering cases as the starting point, emphasize various intelligent weak current systems, and cooperate closely with related majors such as architecture, electromechanical, and decoration, in order to build the hospital into an industry benchmark with advanced functions and complete facilities, and provide people with more convenient, efficient and intelligent medical services.